Baier C, Krastel H, Schapp O, Alexandridis E
Universitäts-Augenklinik Heidelberg.
Ophthalmologe. 1996 Aug;93(4):440-5.
Contact lens electrode ERG is not well tolerated by children. So far, skin electrode ERG has suffered from a weakly defined geometrical relationship to the sources of ERG potentials. Because of the cuplike electric ocular field distribution, skin electrodes were placed: (1) in the middle of the lower eyelid (in order to be positioned in close proximity to the anterior apex of the cornea, which belongs to the electropositive inner surface of the cup); (2) 20 mm laterally to the temporal canthus (in proximity to the cup's electronegative outer surface). (3) Grounding was achieved by attaching a third skin electrode in the forehead midline. Instead of complete dark adaptation, adaptive illumination of 0.1 cd.m-2 was used to avoid frightening the children. After 10 min of adaptation, the examination started. Feeling safe on mother's lap, the little patient looked into a frosted glass screen (about 75 degrees of visual angle, depicting Mickey Mouse) on which a series of strobe flashes was delivered along the lines of the ISCEV ERG Standard: (1) blue flashes: filter no. 625 (Röhm and Haas); repetition rate 0.1 Hz; stimulus strength of white flashes 1.5 cd.m-2 s; (2) red flashes: filter no. S502 (Röhm and Haas); repetition rate 1 Hz; stimulus strength of white flashes 21.75 cd.m-2.s; (3) weak white flashes: stimulus strength 1.5 cd.m-2.s; repetition rate 0.3 Hz; (4) strong white flashes: stimulus strength 11.25 cd.m-2.s; repetition rate 0.3 Hz; (5) white flicker flashes: stimulus strength 1.5 cd.m-2.s; frequency 10, 30, 60 Hz. Recording of single stimulus responses turned out to be feasible; however, to achieve the best results, between 8 and 32 ERG responses were averaged. To illustrate the benefits of skin electrode ERGs in practice, the results of some cases are presented and discussed with respect to clinical findings.
儿童对隐形眼镜电极视网膜电图耐受性不佳。到目前为止,皮肤电极视网膜电图在与视网膜电图电位源的几何关系方面定义不明确。由于杯状眼电场分布,皮肤电极放置位置如下:(1) 在下眼睑中部(以便靠近角膜前顶点,其属于杯状的电正性内表面);(2) 外眦外侧20毫米处(靠近杯状的电负性外表面)。(3) 通过在前额中线粘贴第三个皮肤电极实现接地。为避免吓到儿童,未采用完全暗适应,而是使用0.1 cd.m-2的适应性照明。适应10分钟后开始检查。小患者在母亲腿上感到安全,看着一块磨砂玻璃屏幕(约75度视角,描绘米老鼠),按照国际临床视觉电生理学会(ISCEV)视网膜电图标准,在该屏幕上沿一系列频闪闪光:(1) 蓝色闪光:625号滤光片(罗姆哈斯公司);重复频率0.1 Hz;白色闪光刺激强度1.5 cd.m-2 s;(2) 红色闪光:S502号滤光片(罗姆哈斯公司);重复频率1 Hz;白色闪光刺激强度21.75 cd.m-2.s;(3) 弱白色闪光:刺激强度1.5 cd.m-2.s;重复频率0.3 Hz;(4) 强白色闪光:刺激强度11.25 cd.m-2.s;重复频率0.3 Hz;(5) 白色闪烁闪光:刺激强度1.5 cd.m-2.s;频率10、30、60 Hz。记录单个刺激反应被证明是可行的;然而,为获得最佳结果,对8至32次视网膜电图反应进行了平均。为说明皮肤电极视网膜电图在实际应用中的益处,展示并讨论了一些病例的结果及其临床发现。