Ninomiya H, Chen C H, Onitsuka T, Ichimiya A
Department of Neurophychiatry, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Electroencephalogr Clin Neurophysiol. 1996 Jan;100(1):74-7. doi: 10.1016/0168-5597(95)00160-3.
We investigated the influence of stimulus characteristics and tasks (count and simple reaction tasks) on auditory P50. Ten normal volunteers served as subjects. EEGs and auditory evoked potentials were obtained from Fz, Cz, Pz, C3, C4, T3 and T4 referred to linked earlobes (LE) and balanced non-cephalic (BN) electrodes. In the recordings using a BN reference there were significant negative correlations between the reaction times and P50 peak latencies at Fz, Cz, Pz, C3 and C4. In the LE reference recordings there were negative correlations but these did not reach statistical significance. The results are discussed with reference to the activation of the LE reference and the neural sources of P50. The findings suggest the possibility that reaction times are determined at the very early stage of auditory information processing.
我们研究了刺激特征和任务（计数和简单反应任务）对听觉P50的影响。十名正常志愿者作为受试者。脑电图和听觉诱发电位从Fz、Cz、Pz、C3、C4、T3和T4获取，参考双侧耳垂（LE）和平衡非头颅（BN）电极。在使用BN参考的记录中，Fz、Cz、Pz、C3和C4处的反应时间与P50峰潜伏期之间存在显著负相关。在LE参考记录中存在负相关，但未达到统计学意义。结合LE参考的激活和P50的神经来源对结果进行了讨论。研究结果表明，反应时间可能在听觉信息处理的非常早期阶段就已确定。
