Aloia J F, Vaswani A, Ma R, Flaster E
Department of Medicine, Winthrop University Hospital, Mineola, New York Brookhaven National Laboratories, Upton 11501, USA.
J Clin Endocrinol Metab. 1996 Jun;81(6):2363-9. doi: 10.1210/jcem.81.6.8964878.
The four-compartment model of body composition was studied in 112 healthy black women to develop normative data to be used to assess deviations in illness. Each compartment was measured by an independent method: tritiated water dilution, prompt-gamma neutron activation analysis (for nitrogen), inelastic neutron scattering (for carbon) and dual energy x-ray absorptiometry (for calcium). The mean age of the population was 43.2 years. Race was self-declared. The mean values for the four compartments were [kg SE] protein: 9.6 (0.07); mineral 3.0 (0.03); fat 24.2 (0.70); and water 33.1 (0.29). Each of the compartments changed significantly with age (P < .0001). There were declines in total body water, mineral, and protein, whereas fat increased linearly with age. Linear regressions performed on pre- and postmenopausal women showed a significant difference only for the mineral compartment. Various models were fit to the data to adjust for body size and age. The equation y = age + height + weight fits the data as well as the other models. Equations and graphs were developed to assess each compartment using this linear model and may be used to assess the body composition status of healthy and ill black women. Although black women tended to be heavier than white women, after controlling for differences in body weight (and age) black women had a greater mass of protein, mineral, and water and a similar fat store. These differences, while statistically significant, were not of great magnitude. This was a cross-sectional study and suspected trends with aging must be confirmed by a longitudinal study.
对112名健康黑人女性的身体成分四室模型进行了研究，以制定用于评估疾病偏差的标准数据。每个室通过独立的方法进行测量：氚水稀释法、瞬发γ中子活化分析（用于氮）、非弹性中子散射（用于碳）和双能X线吸收法（用于钙）。研究人群的平均年龄为43.2岁。种族由自我申报。四室的平均值为[kg SE]：蛋白质9.6（0.07）；矿物质3.0（0.03）；脂肪24.2（0.70）；水33.1（0.29）。每个室均随年龄有显著变化（P <.0001）。总体水、矿物质和蛋白质含量下降，而脂肪随年龄呈线性增加。对绝经前和绝经后女性进行的线性回归显示，仅矿物质室存在显著差异。对数据拟合了各种模型以调整身体大小和年龄。方程y =年龄+身高+体重与其他模型一样能很好地拟合数据。利用该线性模型开发了方程和图表来评估每个室，可用于评估健康和患病黑人女性的身体成分状况。尽管黑人女性往往比白人女性更重，但在控制体重（和年龄）差异后，黑人女性的蛋白质、矿物质和水含量更高，脂肪储存量相似。这些差异虽然具有统计学意义，但幅度不大。这是一项横断面研究，怀疑的衰老趋势必须通过纵向研究来证实。
