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女性衰老——身体成分的四室模型

Aging in women--the four-compartment model of body composition.

作者信息

Aloia J F, Vaswani A, Ma R, Flaster E

机构信息

Department of Medicine, Winthrop-University Hospital, Mineola, NY 11501, USA.

出版信息

Metabolism. 1996 Jan;45(1):43-8. doi: 10.1016/s0026-0495(96)90198-5.

DOI:10.1016/s0026-0495(96)90198-5
PMID:8544776
Abstract

The four-compartment model of body composition was examined in 155 white women through measurement of total body carbon (TBC), nitrogen (TBN), calcium (TBCa), and water levels. The age (mean +/- SD) of the population was 51.4 +/- 13.5 years, and values for the four compartments were as follows (in kilograms): protein 8.9 +/- 1.0, water 30.9 +/- 3.5, mineral 2.6 +/- 0.4, and fat 22.6 +/- 7.3. There was a linear change with age for protein and water, whereas mineral and fat were curvilinear. These latter two compartments also showed differences in premenopausal and postmenopausal rates of change. Various models were fit to the data to adjust for body size and age. Each of the four compartments (mineral, water, fat, and protein) changed with age, with fat increasing and the other compartments declining. The equation, y = age + age2 + height + weight, fit the data as well as the other models. Equations are provided to assess body composition in populations with disorders of nutrition, as well as other illnesses, using height, weight, and age as covariates. Since this was a cross-sectional study, longitudinal studies will have to be performed to confirm the accuracy of rates of change with age predicted with each compartment.

摘要

通过测量全身碳(TBC)、氮(TBN)、钙(TBCa)和水分水平,对155名白人女性的身体成分四室模型进行了研究。研究人群的年龄(均值±标准差)为51.4±13.5岁,四室的数值如下(以千克为单位):蛋白质8.9±1.0,水30.9±3.5,矿物质2.6±0.4,脂肪22.6±7.3。蛋白质和水的含量随年龄呈线性变化,而矿物质和脂肪则呈曲线变化。后两个室在绝经前和绝经后的变化率也存在差异。对数据拟合了各种模型以校正身体大小和年龄。四个室(矿物质、水、脂肪和蛋白质)中的每一个都随年龄变化,脂肪增加而其他室减少。方程y =年龄+年龄²+身高+体重与其他模型一样拟合数据。提供了一些方程,以身高、体重和年龄作为协变量,来评估患有营养障碍以及其他疾病的人群的身体成分。由于这是一项横断面研究,因此必须进行纵向研究,以确认每个室预测的年龄变化率的准确性。

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