Langhorst P, Schulz B G, Seller H, Koepchen H P
Institute of Physiology, Free University of Berlin, Germany.
J Auton Nerv Syst. 1996 Mar 7;57(3):149-57. doi: 10.1016/0165-1838(95)00132-8.
The reticular formation of the lower brain stem contains neuronal circuits for the generation of sympathetic tone, respiratory rhythm, muscle tone and the control of vigilance. In anesthetized dogs single neurone activities were recorded in the medial two-thirds of the reticular formation to investigate the organizing principles of this multifunctional system. The results from 110 recordings demonstrate that single neurones receive information from somatosensory afferents of skin, joints and muscles together with afferents from baro-, chemo- and lung inflation and deflation receptors. Whereas the composition of afferent spectra from somatosensory sources was different from neurone to neurone, baroreceptors had a more generalized activity-decreasing effect and chemoreceptors had a generalized activity-increasing influence, the former directing physiological systems to a trophotropic and the latter towards an ergotropic state. The functional significance of the results for the co-ordination of different physiological systems is discussed.
脑干下部的网状结构包含用于产生交感神经张力、呼吸节律、肌肉张力以及控制警觉性的神经回路。在麻醉的狗身上，记录了网状结构内侧三分之二区域的单个神经元活动，以研究这个多功能系统的组织原则。110次记录的结果表明，单个神经元接收来自皮肤、关节和肌肉的体感传入信息，以及来自压力感受器、化学感受器和肺扩张与收缩感受器的传入信息。虽然来自体感源的传入频谱组成因神经元而异，但压力感受器具有更普遍的活动降低作用，化学感受器具有普遍的活动增加影响，前者将生理系统导向营养性状态，后者导向应激性状态。讨论了这些结果对不同生理系统协调的功能意义。
