Grote J, Laue O, Eiring P, Wehler M
Department of Physiology, University of Bonn, Germany.
J Auton Nerv Syst. 1996 Mar 7;57(3):168-72. doi: 10.1016/0165-1838(95)00096-8.
Tissue PO2 distribution was measured in rat cerebral cortex during arterial normoxia and arterial hypoxia. The study was designed to examine the relationship between the PO2 histograms determined with surface electrodes in the superficial cortical cells and with needle electrodes in the cortical laminae below. Under normoxic as well as under hypoxic conditions the PO2 distributions of the compared brain regions were in close agreement. The results indicate that PO2 measurements in the brain cortex with surface microelectrodes give a correct view over the tissue oxygenation in cortical regions up to 500 microns below the measuring field.
在动脉正常氧合和动脉缺氧期间，测量大鼠大脑皮质中的组织氧分压分布。本研究旨在检查用表面电极测定的浅层皮质细胞中的氧分压直方图与用针电极测定的下方皮质层中的氧分压直方图之间的关系。在常氧和缺氧条件下，所比较脑区的氧分压分布密切一致。结果表明，用表面微电极测量大脑皮质中的氧分压能正确反映测量区域下方达500微米的皮质区域的组织氧合情况。
