Iwafuchi M, Watanabe H
Department of Medical Technology, College of Biomedical Technology of Niigata.
Nihon Rinsho. 1996 May;54(5):1217-23.
Synchronous multiple early gastric cancer (SMEGC) was found in 202(20.9%) of 966 surgically resected primary early gastric cancer (EGC). The incidence of SMEGC clinically diagnosed was 9.0%, and that increased to 19.3% by pathological macroscopical examine. SMEGC was more frequent in male patients than in female patients. Patients older than 60 years old occupied 80.7% of SMEGC. 72.8% of SMEGC had two and 27.2% had more than three EGC. 56.7% of SMEGC had intramucosal cancers, 36.4% had submucosa-invasing and intramucosal cancer, and 6.9% had submucosa-invasing cancers. In 78.7% of SMEGC, the main and associated cancer were composed of differentiated type adenocarcinoma, 20.7% of SMEGC synchronously contained gastric adenoma. We should be cautious that other EGC may be present when preoperative diagnosing the patients with EGC and macroscopical examining the resected stomach.
在966例接受手术切除的原发性早期胃癌(EGC)患者中,发现202例(20.9%)为同步多发早期胃癌(SMEGC)。临床诊断的SMEGC发生率为9.0%,经病理宏观检查后该发生率升至19.3%。SMEGC在男性患者中比在女性患者中更常见。60岁以上的患者占SMEGC的80.7%。72.8%的SMEGC有两处EGC,27.2%有三处以上EGC。56.7%的SMEGC为黏膜内癌,36.4%为侵犯黏膜下层的黏膜内癌,6.9%为侵犯黏膜下层的癌。在78.7%的SMEGC中,主要癌灶和相关癌灶均为分化型腺癌,20.7%的SMEGC同时含有胃腺瘤。在术前诊断EGC患者并对切除的胃进行宏观检查时,我们应警惕可能存在其他EGC。