Kitagawa H, Nagakawa T, Ueno K, Ohta T, Kayahara M, Miyazaki I
Department of Surgery(II), School of Medicine, Kanazawa University.
Nihon Rinsho. 1996 May;54(5):1385-9.
Early carcinoma of the biliary tract was defined as cancer cell invasion limited to the mucosal or muscularis propria in the case of the gallbladder, to the mucosal or fibro-muscular layer in the case of carcinoma of the bile duct and to the sphincter of Oddi in the case of the papilla of Vater from a study on the correlation between the depth of cancer invasion and the result of surgery. A few cases, however, have lymph node metastasis, venous invasion, perineural infiltration or involvement of the lymphatic vessels. The surgical procedures should therefore be selected in order to have a good chance for long-term survival. The importance of systematic lymph node dissection to improve survival is emphasize, even in patients with early biliary tract cancer.
根据一项关于癌症浸润深度与手术结果相关性的研究,早期胆道癌的定义为:胆囊癌时癌细胞浸润局限于黏膜层或固有肌层;胆管癌时癌细胞浸润局限于黏膜层或纤维肌层; Vater乳头癌时癌细胞浸润局限于Oddi括约肌。然而,少数病例存在淋巴结转移、静脉侵犯、神经周围浸润或淋巴管受累。因此,应选择手术方式以获得良好的长期生存机会。即使对于早期胆道癌患者,也强调系统性淋巴结清扫对提高生存率的重要性。