Kawayama T, Sawa A, Sueyasu Y, Arikawa K, Shiraishi T, Ichikawa Y, Oizumi K
First Department of Internal Medicine, Kurume University School of Medicine, Fukuoka, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1996 Aug;34(8):911-5.
We encountered a case of chronic pulmonary paracoccidiodomycosis in Japan. A 53-year-old Japanese man, who had worked in Brazil from 1964 to 1969. Came to our hospital because of abnormal shadows on a screening chest roentgenogram. In 1989, he had been treated with fluconazole for mucocutaneous-lymphangitic paracoccidioidomycosis with oral ulceration and neak hymphadenitis. Chest roentgenograms and computed tomograms showed diffuse small nodular and emphysematous shadows. Microscopical examination of specimens obtained by transbronchial lung biopsy showed no abnormality. He was treated with oral fluconazole, and the abnormal radiographic shadows regressed. We believe that this was the first case of chronic pulmonary paracoccidiodomycosis in Japan.
我们在日本遇到了一例慢性肺副球孢子菌病病例。一名53岁的日本男性,曾于1964年至1969年在巴西工作。因胸部X线筛查发现异常阴影而来我院就诊。1989年,他曾因伴有口腔溃疡和颈部淋巴结炎的皮肤黏膜淋巴管型副球孢子菌病接受氟康唑治疗。胸部X线片和计算机断层扫描显示弥漫性小结节和肺气肿阴影。经支气管肺活检获取的标本显微镜检查未发现异常。他接受了口服氟康唑治疗,影像学异常阴影消退。我们认为这是日本首例慢性肺副球孢子菌病病例。