Iukhtin V I, Khripun A I, Raksha A P, Zhukotskiĭ A V, Sergeeva N A, Dorofeeva I M, Belous G G
Khirurgiia (Mosk). 1996(3):53-6.
Specific morphological and functional changes in the liver in acute obturative cholecystitis have been experimentally studied in 30 dogs and clinically examined in 21 patients. No morphological substrate of liver insufficiency were found in early period of acute obturative cholecystitis. Early changes in the liver are of reactive nature and have the features of active nonspecific hepatitis. The reactions of compensation and decompensation are changing each other periodically. The intensive reactions of compensation take place in the first 2 or 3 days of disease. The reactions of compensation weaken gradually. There is no correlation between changes in the liver and in blood serum. The early surgery and laparoscopic procedures in acute obturative cholecystitis are advocated.
对30只犬进行了实验研究，对21例患者进行了临床检查，以观察急性闭襻性胆囊炎时肝脏的特定形态学和功能变化。在急性闭襻性胆囊炎早期未发现肝功能不全的形态学基础。肝脏的早期变化具有反应性，具有活动性非特异性肝炎的特征。代偿和失代偿反应周期性相互变化。在疾病的最初2或3天会出现强烈的代偿反应。代偿反应逐渐减弱。肝脏变化与血清变化之间无相关性。提倡对急性闭襻性胆囊炎进行早期手术和腹腔镜手术。
