Amendolara M, Perri S, Pasquale E, Biasiato R
U.O.A. di Chirurgia di Monselice A.S.L. 17 Conselve-Este-Monselice-Montagnana (PD), Università di L'Aquila.
Chir Ital. 2001 May-Jun;53(3):375-81.
The aim of the study was to demonstrate the importance of early laparoscopic cholecystectomy for acute cholecystitis, without "conservative" treatment (intravenous fluids and antibiotics for 48-72 hours) to reduce inflammation. Early laparoscopic cholecystectomy reduces bile duct injury and the percentage of conversion to open cholecystectomy. Thirty-five patients with acute cholecystitis were submitted to early laparoscopic cholecystectomy, equally divided according to sex. All patients were submitted to US scans preoperatively and operated on by surgeons skilled in emergency laparoscopic operative techniques. Laparoscopic cholecystectomy was always performed with 4 trochars and the use of a 30 degrees laparoscope. Technical modifications during early laparoscopic cholecystectomy were drainage and decompression with subsequent de-tension and distention of the gallbladder. These manoeuvres entailed the use of Babcock, Endopatch (Ethicon) atraumatic forceps. In the presence of acute gallbladder inflammation we dissect the gall-blader well with a suction-irrigation tube. In patients suspected of having common bile duct stones, biliary duct injuries and/or anatomical changes due to inflammation, we perform intraoperative cholangiography. Five patients had conversion to open cholecystectomy (14.2%), in two cases (5.7%) for concomitant choledochal stones, in two cases (5.7%) for biliary peritonitis and in the fifth case (2.8%) for severe empyema of the gallbladder. Laparoscopic cholecystectomy was performed in 20 patients for acute cholecystitis (57.1%), in 9 patients for empyema (25.7%) and in 6 patients for gangrenous cholecystitis. Four cases presented postoperative complications owing to bile leakage from the liver bed, treated with antibiotic therapy. One patient presented jaundice on day 30 after laparoscopy owing to inadequate positioning of the clips on the cystic duct, near the common bile duct; ERCP was performed with application of a prosthesis, which was removed after two months. Our experience and results support the validity of early laparoscopic cholecystectomy in the treatment of acute cholecystitis, because it reduces the postoperative length of hospital stay and hospital costs. Early treatment is always helpful for inflamed and oedematous tissue which favours dissection, while dense, fibrotic adhesions hinder regular dissection with a greater risk of injury to the biliary duct and and a higher conversion rate to open cholecystectomy.
本研究的目的是证明早期腹腔镜胆囊切除术对于急性胆囊炎的重要性,不采用“保守”治疗(静脉输液和抗生素治疗48 - 72小时)来减轻炎症。早期腹腔镜胆囊切除术可减少胆管损伤以及中转开腹胆囊切除术的比例。35例急性胆囊炎患者接受了早期腹腔镜胆囊切除术,按性别平均分组。所有患者术前均接受超声扫描,并由熟练掌握急诊腹腔镜手术技术的外科医生进行手术。腹腔镜胆囊切除术始终使用4个套管针,并使用30度腹腔镜。早期腹腔镜胆囊切除术期间的技术改进包括引流和减压,随后对胆囊进行去张力和扩张。这些操作需要使用巴布科克钳、爱惜康(Ethicon)无损伤钳。在存在急性胆囊炎症的情况下,我们用吸引冲洗管仔细分离胆囊。对于怀疑有胆总管结石、胆管损伤和/或因炎症导致解剖结构改变的患者,我们进行术中胆管造影。5例患者中转开腹胆囊切除术(14.2%),2例(5.7%)是因为合并胆总管结石,2例(5.7%)是因为胆汁性腹膜炎,第5例(2.8%)是因为严重的胆囊积脓。20例患者因急性胆囊炎接受腹腔镜胆囊切除术(57.1%),9例因积脓(25.7%),6例因坏疽性胆囊炎。4例患者因肝床胆汁漏出现术后并发症,经抗生素治疗。1例患者在腹腔镜检查后第30天出现黄疸,原因是胆囊管夹在胆总管附近放置不当;进行了内镜逆行胰胆管造影(ERCP)并置入了假体,两个月后取出。我们的经验和结果支持早期腹腔镜胆囊切除术治疗急性胆囊炎的有效性,因为它缩短了术后住院时间并降低了住院费用。早期治疗对炎症和水肿组织总是有帮助的,有利于分离,而致密的纤维化粘连会阻碍常规分离,增加胆管损伤风险和中转开腹胆囊切除术的比例。