Kos M, Ljubojević N, Ilić-Forko J, Babić D, Jukić S
Zavod za ginekolosku, perinatalnu patologiju, Zagreb.
Lijec Vjesn. 1996 Jul-Aug;118(7-8):158-60.
A patient with vulvar elephantiasis, which had been developing since 1985 when biopsy was first performed showing only signs of chronic inflammation, is described. From 1985-1987 (when she was first admitted to the hospital) microbiological analyses were negative and antibiotic therapy was administered without success. At the first admittance abscess of the left Bartholin's gland and furunculosis of vulva were diagnosed. Serological tests to agents that usually cause vulval infections with elephantiasis were negative, and microbiological analyses revealed mixed bacterial flora. Biopsy showed again only nonspecific chronic inflammation. The patient received ampicyllin, oxytetracyclin and doxycillin. She did not return for the control until 1993. At that time the vulvar mass reached 16:13:10 cm and was surgically removed. The histological picture showed chronic granulomatous inflammation. The results of microbiological and serological tests were again the same as before.
本文描述了一位患有外阴象皮肿的患者,自1985年首次进行活检仅显示慢性炎症迹象以来,病情一直在发展。1985年至1987年(她首次入院时),微生物分析呈阴性,抗生素治疗无效。首次入院时,诊断为左侧巴氏腺脓肿和外阴疖病。针对通常导致外阴感染并引发象皮肿的病原体的血清学检测呈阴性,微生物分析显示为混合菌群。活检再次仅显示非特异性慢性炎症。患者接受了氨苄青霉素、土霉素和强力霉素治疗。直到1993年她才回来复查。当时外阴肿物大小为16:13:10厘米,遂进行了手术切除。组织学检查显示为慢性肉芽肿性炎症。微生物学和血清学检测结果再次与之前相同。