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[婴儿腹绞痛的管理]

[Management of infantile colics].

作者信息

Savino F, Oggero R

机构信息

Clinica Pediatrica, Ospedale Infantile, Regina Margherita, Università degli studi, Torino.

出版信息

Minerva Pediatr. 1996 Jul-Aug;48(7-8):313-9.

PMID:8965762
Abstract

UNLABELLED

Infantile colic concerns about 10-30% of all newborns and has been defined as a condition characterized by paroxysmal episodes of unexplained full force crying for at least three days a week and continuing for one week or more in a thriving well-nourished infant. The disorder more likely occurs in the evening, without identifiable causes and resolves spontaneously by the fourth month of life. The several factors involved in the etiopathogenesis (food intolerance or allergy to cow's milk protein, intolerance to lactose, intestinal hyperperistalsis, neuro-hormonal immaturity, maternal anxiety and familial stress), make the management of infants with colics difficult. We propose a scoring system for the evaluation of colics in infants based on: 1) crying intensity and duration; 2) accompanying characteristics of crises (e.g. meteorism, family history for allergic disease, type of feeding, type of stools); 3) evaluation of parents' opinion of their infants' crying. Type of management is based on the score: a) crying that is unrelated to colics: treatments referred to specific diagnosis. b) crying that is related to colics but not severe: first and second step of management; c) crying that is related to colics and is severe: third step of management.

MANAGEMENT

first step: pacifier, rocking, dull continuous background noise, hot water bottle on the abdomen, herbal tea, simethicone. Second step: pharmacological treatment and periodic controls. Pharmacological treatment include antispastic drugs (e.g. cimetropium bromide). Third step: dietary modification and/or pharmacological treatment: mothers of breast-fed infants are given a diet with no milk or products containing its proteins, or fish, or eggs. Infants who are not breast-fed receive soy milk and if symptoms continue soy milk is substituted with hydrolyzed casein milk formula. Pharmacological treatment include antispastic drugs (e.g. cimetropium bromide and in non responders dicyclomine hydrochloride). Dietary modifications appear more suitable than pharmacological treatment in resolving symptoms, since side effects of drugs have been described and our recent results indicate appropriate dietary modifications offer better results than pharmacological treatment in resolving crises. However, before interrupting dietary modifications and reintroducing cow's milk proteins, infant's tolerance to such proteins is tested. In any case because of the good prognosis and rapid regression of symptoms, dietary regimens or pharmacological treatment should only be applied if really necessary and for brief periods under medical supervision.

摘要

未标注

婴儿腹绞痛困扰着10%至30%的新生儿,其被定义为一种以阵发性发作、无法解释的剧烈哭闹为特征的病症,每周至少持续三天,且在发育良好、营养充足的婴儿中持续一周或更长时间。这种病症更易在晚上发作,无明确病因,通常在婴儿四个月大时自行缓解。病因发病机制涉及多个因素(对牛奶蛋白的食物不耐受或过敏、乳糖不耐受、肠道蠕动亢进、神经激素不成熟、母亲焦虑和家庭压力),使得腹绞痛婴儿的治疗颇具难度。我们提出一种基于以下方面对婴儿腹绞痛进行评估的评分系统:1)哭闹强度和持续时间;2)发作的伴随特征(如腹胀、过敏性疾病家族史、喂养方式、大便类型);3)对父母关于其婴儿哭闹看法的评估。治疗方式依据评分而定:a)与腹绞痛无关的哭闹:针对具体诊断进行治疗。b)与腹绞痛相关但不严重的哭闹:治疗的第一步和第二步;c)与腹绞痛相关且严重的哭闹:治疗的第三步。

治疗

第一步:安抚奶嘴、摇晃、低沉持续的背景噪音、腹部放置热水袋、凉茶、西甲硅油。第二步:药物治疗及定期检查。药物治疗包括抗痉挛药物(如溴化西托溴铵)。第三步:饮食调整和/或药物治疗:母乳喂养婴儿的母亲采用不含牛奶或含牛奶蛋白产品、鱼或鸡蛋的饮食。非母乳喂养的婴儿饮用豆奶,若症状持续,则用酪蛋白水解配方奶替代豆奶。药物治疗包括抗痉挛药物(如溴化西托溴铵,对无反应者使用盐酸双环胺)。饮食调整在缓解症状方面似乎比药物治疗更合适,因为已描述了药物的副作用,且我们最近的结果表明,适当的饮食调整在缓解发作方面比药物治疗效果更好。然而,在中断饮食调整并重新引入牛奶蛋白之前,需检测婴儿对这些蛋白的耐受性。无论如何,鉴于预后良好且症状迅速消退,饮食方案或药物治疗仅在确实必要且在医疗监督下短期应用。

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[Management of infantile colics].[婴儿腹绞痛的管理]
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