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1996年美国儿童中的艾滋病情况

AIDS among children--United States, 1996.

出版信息

MMWR Morb Mortal Wkly Rep. 1996 Nov 22;45(46):1005-10.

PMID:8965798
Abstract

As of September 30, 1996, a total of 566,002 acquired immunodeficiency syndrome (AIDS) cases, including 7472 cases among children ages < 13 years (1%), had been reported to CDC by state and territorial health departments. Most children reported with AIDS acquired human immunodeficiency virus (HIV) infection perinatally from their mothers. During 1988-1993, an estimated 6000-7000 children were born each year to HIV-infected women; an estimated 1000-2000 of these children were infected annually. In 1994, results of clinical trials demonstrating effective therapy for reducing perinatal HIV transmission indicated a two-thirds decrease in such transmission associated with zidovudine (ZDV) therapy for HIV-infected pregnant women and their newborns. The Public Health Service (PHS) issued recommendations in 1994 for ZDV treatment to reduce perinatal HIV transmission, and in 1995 for routine HIV counseling and voluntary testing for all pregnant women in the United States. This report summarizes the epidemiology of AIDS in children in the United States reported cumulatively from 1982 through September 1996, presents rates for 1995 (the most recent year for which census estimates are available), and describes a recent decrease in the rate of perinatally acquired AIDS.

摘要

截至1996年9月30日,各州及领地卫生部门共向美国疾病控制与预防中心(CDC)报告了566,002例获得性免疫缺陷综合征(艾滋病)病例,其中13岁以下儿童有7472例(占1%)。报告的大多数艾滋病患儿是在出生时从母亲那里感染了人类免疫缺陷病毒(HIV)。在1988 - 1993年期间,估计每年有6000 - 7000名儿童由感染HIV的妇女所生;其中估计每年有1000 - 2000名儿童被感染。1994年,临床试验结果表明有效治疗可减少围产期HIV传播,这显示与齐多夫定(ZDV)治疗HIV感染孕妇及其新生儿相关的此类传播减少了三分之二。公共卫生服务部(PHS)于1994年发布了关于使用ZDV治疗以减少围产期HIV传播的建议,并于1995年发布了关于对美国所有孕妇进行常规HIV咨询和自愿检测的建议。本报告总结了1982年至1996年9月美国累计报告的儿童艾滋病流行病学情况,列出了1995年(可获得人口普查估计数的最近一年)的发病率,并描述了近期围产期获得性艾滋病发病率的下降情况。

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