Pfeffer-Baczuk A, Barcikowska M, Karwańska A
Zakładu Neuropatologii, Centrum Medycyny Doświadczalnej i Klinicznej PAN w Warszawie.
Neurol Neurochir Pol. 1996 May-Jun;30(3):389-98.
Extrapyramidal signs were assessed in 112 patients satisfying NINCDS/ADRDA criteria for probable Alzheimer's disease. They were present in 50% of the patients. The most common features of them were bradykinesia and rigidity. Resting tremor was rarely encountered. There were no significant differences in age of onset, symptom duration, presence of primitive reflexes and psychotic symptoms between cases with and without extrapyramidal signs, while the presence of extrapyramidal signs was associated with statistically significant greater dementia severity.
对112名符合NINCDS/ADRDA可能阿尔茨海默病标准的患者进行了锥体外系体征评估。50%的患者存在锥体外系体征。其最常见的特征是运动迟缓及僵硬。静止性震颤很少见。有锥体外系体征和无锥体外系体征的患者在发病年龄、症状持续时间、原始反射及精神症状的存在方面无显著差异，而锥体外系体征的存在与痴呆严重程度在统计学上显著更高相关。
