Michałkiewicz J, Nowacka K, Stachowski J, Gregorek H, Madaliński K
Dział Immunologii Klinicznej Centrum Zdrowia Dziecka w Warszawie.
Pediatr Pol. 1996 Jan;71(1):47-56.
Some of CD4+ helper T cells-mediated mechanisms of IgE synthesis were discussed. The present division of helper T cells population into Th1 and Th2 subsets reflects their role in the induction as well as in the control of immune response. The Th1 cells are involved mainly in the cellular immune responses, and Th2 cells in the humoral immune responses, including IgE synthesis. Development of investigations on cytokines and evaluation of their influence on regulation of IgE synthesis may have a role in the treatment of allergic diseases in the future.
讨论了一些CD4+辅助性T细胞介导的IgE合成机制。目前将辅助性T细胞群体分为Th1和Th2亚群，这反映了它们在免疫反应的诱导和控制中的作用。Th1细胞主要参与细胞免疫反应，而Th2细胞参与体液免疫反应，包括IgE合成。细胞因子研究的进展及其对IgE合成调节影响的评估，可能在未来过敏性疾病的治疗中发挥作用。
