Krivitskaia V Z, Iakovleva N V, Aleksandrova N I
Vopr Virusol. 1996 Sep-Oct;41(5):234-7.
Specific humoral immune response has been studied in 8 patients with chronic obstructive bronchitis, in whom the persistence of RSV was detected, and in a group of patients without RSV persistence. Humoral immunity in patients with RSV persistence vs. those with acute and chronic bronchitis without viral persistence was characterized by the following features: a) earlier and more active production of IgG and, even more so, IgM and IgA; b) long persistence of high titers of anti-RSV IgG, IgM, and IgA-up to 17, 28, and 30 weeks, respectively; c) low anti-RSV neutralizing activity of serum antibodies.
对8例检测到呼吸道合胞病毒（RSV）持续存在的慢性阻塞性支气管炎患者以及一组未检测到RSV持续存在的患者的特异性体液免疫反应进行了研究。与急性和慢性支气管炎但无病毒持续存在的患者相比，RSV持续存在患者的体液免疫具有以下特征：a）IgG产生更早且更活跃，IgM和IgA更是如此；b）抗RSV IgG、IgM和IgA高滴度长期持续存在，分别长达17周、28周和30周；c）血清抗体的抗RSV中和活性较低。
