Boldt J, Müller M, Uphus D, Hempelmann G
Abteilung Anaesthesiologie und Operative Intensivmedizin, Justus-Liebig-Universität Giessen.
Anaesthesist. 1996 Aug;45(8):731-6. doi: 10.1007/s001010050305.
Cost control is no longer an option, but a necessity. Propofol anaesthesia is expensive, however, the true differences in comparison to volatile anaesthetics (isoflurane) are not known.
Sixty patients undergoing either thyroidectomy (n = 30) or laparoscopic cholecystectomy (n = 30) were randomly divided into 3 groups of 20 patients. In group I propofol and fentanyl were used for anaesthesia, in group II isoflurane ('standard' isoflurane anaesthesia), and in group III isoflurane using a low-flow system (fresh gas flow 2 l/min) was given. All patients were ventilated using 70% N2O in oxygen. Vecuronium was used in all cases for muscle relaxation. Isoflurane consumption was measured by weighing the isoflurane vaporizer.
Biometric data and time of administration of the anaesthetic were similar in the three groups. Propofol patients stayed significantly shorter than isoflurane patients in the postanaesthesia care unit (PACU). Costs of additional drugs (antiemetics, analgesics) in the PACU were least in the propofol patients. Costs were without differences between the propofol (78.30 DM/patient) and 'standard' isoflurane groups (81.69 DM/patient). Patients in group III showed the lowest overall costs (57.46 DM/patient) (P < 0.05).
A climate of cost-consciousness and cost-containment prevails at the present time. The costs of propofol and 'standard' isoflurane anaesthesia were without differences; however, isoflurane used in a low-flow system had the lowest cost in this study. Doubts are justified, however, as to whether the choice of anaesthetic agents may considerably lower the costs of an anaesthesia department.
成本控制已不再是一种选择,而是一种必需。丙泊酚麻醉费用高昂,然而,与挥发性麻醉剂(异氟烷)相比的真正差异尚不清楚。
60例行甲状腺切除术(n = 30)或腹腔镜胆囊切除术(n = 30)的患者被随机分为3组,每组20例。第一组使用丙泊酚和芬太尼进行麻醉,第二组使用异氟烷(“标准”异氟烷麻醉),第三组使用低流量系统(新鲜气流2升/分钟)给予异氟烷。所有患者均使用70%氧化亚氮和氧气进行通气。所有病例均使用维库溴铵进行肌肉松弛。通过称量异氟烷蒸发器来测量异氟烷消耗量。
三组患者的生物统计学数据和麻醉给药时间相似。丙泊酚麻醉的患者在麻醉后护理单元(PACU)停留的时间明显短于异氟烷麻醉的患者。PACU中额外药物(止吐药、镇痛药)的费用在丙泊酚麻醉患者中最低。丙泊酚组(78.30德国马克/患者)和“标准”异氟烷组(81.69德国马克/患者)的费用无差异。第三组患者的总体费用最低(57.46德国马克/患者)(P < 0.05)。
目前存在注重成本和控制成本的氛围。丙泊酚麻醉和“标准”异氟烷麻醉的费用无差异;然而,在本研究中,使用低流量系统的异氟烷成本最低。然而,麻醉剂的选择是否能显著降低麻醉科的成本仍值得怀疑。