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[Rubomycin Q1--an anthracycline metabolite from Streptomyces coeruleorubidus 2679, a strain producing rubomycin C].

作者信息

Fedorova G B, Golova T P, Arkhangel'skaia N M, Lazhko E I, Abramova E A, Bychkova O P, Polunin A D, Katrukha G S

出版信息

Antibiot Khimioter. 1996 Mar;41(3):3-8.

PMID:8967800
Abstract

In the programme of screening of biologically active secondary metabolites produced by Streptomyces coeruleorubidus 2679 a new reddish-violet component (rubomycin Q1) with antibacterial and cytotoxic activity was isolated from the culture fluid of the organism. Some physico-chemical and biological properties of a chromatographically pure rubomycin Q1 were investigated. It was shown with the use of 1H NMR, UV, IR and mass spectrometry that rubomycin Q1 was an anthracycline antibiotic (9,10-anhydro-13-desoxycarminomycin).

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