Badeva B, Kostadinova R, Shtereva K, Radichkova V, Kazakov K, Petrov P
Khirurgiia (Sofiia). 1996;49(4):12-3.
It is the purpose of the study to outline the superiorities of combined anesthesia in 100 patients undergoing orthopaedic (25 cases) and orthopaedic surgery (75 cases) interventions. The average duration of the operation is 90 +/- 25 min, performed under continuous peripheral (40 patients) and central (60 patients) nerve block, using Propofol against the background of continuous i.v. infusion and spontaneous ventilation. Nerve block is done according to routinely adopted techniques. The initial infusion rate for propofol (Diprivan) is 5 +/- 1.3 mg/kg/h, followed by infusional rate securing sedation II-III degree according to Ramsey's scale (mean 4 +/- 1.2 mg/kg/h). In 92 per cent of patients the sedation level is estimated as very good. In 8 per cent switching over to TIVA (total intravenous anesthesia) is necessitated because of the incomplete nerve block. No cases of hypotension or other essential secondary effects are recorded. Subjectively the anesthesiological technique is accepted as very good by most of the patients.
本研究旨在概述联合麻醉在100例接受骨科（25例）和矫形外科手术（75例）干预患者中的优势。手术平均时长为90±25分钟，在连续外周神经阻滞（40例患者）和连续中枢神经阻滞（60例患者）下进行，在持续静脉输注和自主通气背景下使用丙泊酚。神经阻滞按照常规采用的技术进行。丙泊酚（得普利麻）初始输注速率为5±1.3毫克/千克/小时，随后根据拉姆齐量表确保达到Ⅱ - Ⅲ级镇静的输注速率（平均4±1.2毫克/千克/小时）。92%的患者镇静水平评估为非常好。8%的患者因神经阻滞不完全而需要转换为全凭静脉麻醉（TIVA）。未记录到低血压或其他重要的继发效应病例。大多数患者主观上认为麻醉技术非常好。
