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男性酗酒者继发性抑郁的病因学

Aetiology of secondary depression in male alcoholics.

作者信息

Roy A

机构信息

Department of Veterans Affairs Medical Center, Dept. of Psychiatry 116A, East Orange, New Jersey 07018, USA.

出版信息

Br J Psychiatry. 1996 Dec;169(6):753-7. doi: 10.1192/bjp.169.6.753.

Abstract

BACKGROUND

Secondary depression is common among primary alcoholics. However, its aetiology is poorly understood.

METHOD

Forty men with primary alcoholism, abstinent for two weeks or more, with a secondary major depressive episode were compared with forty matched never-depressed primary alcoholic controls for risk factors for depression and recent life events.

RESULTS

In the six months before the onset of depression depressed alcoholics had experienced significantly more life events, more life events with negative impact, more dependent events caused by alcohol, and more independent events. Significantly more depressed alcoholics than controls had a family history of depression, a family history of suicidal behaviour and had themselves attempted suicide.

CONCLUSION

Having recent life events, particularly events with negative impact, and a family history of depression are risk factors for secondary depression in alcoholics.

摘要

背景

继发性抑郁症在原发性酗酒者中很常见。然而,其病因尚不清楚。

方法

将40名患有继发性重度抑郁发作且已戒酒两周或更长时间的原发性酗酒男性与40名匹配的从未患过抑郁症的原发性酗酒对照者进行比较,以分析抑郁症的危险因素和近期生活事件。

结果

在抑郁症发作前的六个月里,抑郁的酗酒者经历了明显更多的生活事件、更多具有负面影响的生活事件、更多由酒精导致的依赖事件以及更多独立事件。与对照组相比,明显更多的抑郁酗酒者有抑郁症家族史、自杀行为家族史且曾尝试自杀。

结论

近期发生生活事件,尤其是具有负面影响的事件,以及抑郁症家族史是酗酒者继发性抑郁症的危险因素。

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