Murphy J R
Eli Lilly and Company, Indianapolis, Indiana 46285, USA.
J Biopharm Stat. 1996 Nov;6(4):477-94. doi: 10.1080/10543409608835157.
Uniform matrix designs for drug stability studies are introduced and compared to standard matrix designs. Comparisons are made on the basis of design moment, D-efficiency, uncertainty, G-efficiency, and statistical power. It is shown that uniform matrix designs provide superior statistical properties with the same or fewer design points than standard matrix designs.
