Guo X, Johnson W D
Department of Biometry and Genetics, Louisiana State University Medical Center, New Orleans 70112-1393, USA.
J Biopharm Stat. 1996 May;6(2):155-76. doi: 10.1080/10543409608835130.
Procedures for determining sample size in multivariate repeated measures experiments are discussed. The focus is on designs with either one group or two independent groups of subjects, the point of departure being multivariate repeated measures. Determination of the minimum sample size required is based on power considerations associated with Hotelling's T2 and the F-test. We first consider procedures for determining sample size assuming an arbitrary covariance matrix. The special case where we assume that the transformed data have a multivariate spherical covariance matrix is also considered. Tables of the minimum sample sizes required for several hypotheses from multivariate analysis are presented.
讨论了多变量重复测量实验中样本量的确定方法。重点在于单组或两组独立受试者的设计，出发点是多变量重复测量。所需最小样本量的确定基于与霍特林T2和F检验相关的功效考量。我们首先考虑在假设任意协方差矩阵的情况下确定样本量的方法。还考虑了假设变换后的数据具有多变量球形协方差矩阵的特殊情况。给出了多变量分析中几个假设所需最小样本量的表格。
