Nakano S, Kuramochi S, Hosoda Y, Miura S
Department of Pathology, Saga Medical School, Japan.
Pathol Int. 1996 Nov;46(11):883-6. doi: 10.1111/j.1440-1827.1996.tb03562.x.
An autopsy case of a 74-year-old man suffering from edema in the legs and diagnosed as protein-losing enteropathy due to intestinal lymphangiectasia is presented. He underwent a radical operation and radiotherapy for esophageal carcinoma at age 65 years and the onset of protein-losing enteropathy was at age 70. Postmortem examination disclosed widespread abnormalities of the duodenal and small intestinal lymphatics and mesenteric lymph node fibrosis. The mucosal lymphatic capillaries were markedly dilated. In the submucosal and serosal layers, the lymphatic vessels showed marked dilatation in some areas and fibrous occlusion with very thick muscle layers in others. All these lymphatic changes were presumed to be attributable to a reactive process secondary to lymph congestion, which it is suggested, was caused by the mesenteric lymph node fibrosis.
本文报告一例74岁男性尸检病例，该患者有腿部水肿，诊断为肠淋巴管扩张症所致的蛋白丢失性肠病。他65岁时因食管癌接受了根治性手术和放疗，70岁时出现蛋白丢失性肠病。尸检发现十二指肠和小肠淋巴管广泛异常，肠系膜淋巴结纤维化。黏膜淋巴管明显扩张。在黏膜下层和浆膜层，淋巴管在某些区域明显扩张，而在其他区域则有纤维性闭塞且肌层很厚。所有这些淋巴改变被认为是继发于淋巴充血的反应性过程所致，提示淋巴充血是由肠系膜淋巴结纤维化引起的。
