Ahrens T S, Beattie S, Nienhaus T
AACN Clin Issues. 1996 Nov;7(4):507-18. doi: 10.1097/00044067-199611000-00005.
Many conventional therapies are designed to treat acute lung injury. Although evidence exists that improved outcomes are a result of these therapies, mortality remains high in this population. Perhaps one of the key reasons why mortality remains high in the failing lung population is that current therapies do not "cure" the problem; current therapies are designed to support the lung, rather than fix the pulmonary problem. In this paper, a review of new and experimental therapies to support the failing lung are presented. Therapies such as prone positioning, nitric oxide, and mediator therapies are addressed. It is likely that newer therapies offer the most hope for improving the high mortality associated with acute lung injury.
许多传统疗法旨在治疗急性肺损伤。尽管有证据表明这些疗法能带来更好的治疗效果，但该人群的死亡率仍然很高。肺功能衰竭人群死亡率居高不下的一个关键原因可能是，当前的疗法并未“治愈”问题；当前疗法旨在支持肺部，而非解决肺部问题。本文对支持肺功能衰竭的新疗法和实验性疗法进行了综述。文中探讨了诸如俯卧位通气、一氧化氮和介质疗法等治疗方法。更新的疗法很可能为改善与急性肺损伤相关的高死亡率带来最大希望。
