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对23例头颈部结核患者的回顾。

A review of 23 patients with tuberculosis of the head and neck.

作者信息

Penfold C N, Revington P J

机构信息

Oral and Facial Surgery Unit, Glan Clwyd Hospital, Rhyl, UK.

出版信息

Br J Oral Maxillofac Surg. 1996 Dec;34(6):508-10. doi: 10.1016/s0266-4356(96)90246-6.

DOI:10.1016/s0266-4356(96)90246-6
PMID:8971444
Abstract

OBJECTIVE

to review the clinical features and management of tuberculosis of the head and neck and to identify those features which may aid diagnosis.

DESIGN

retrospective study.

SETTING

teaching hospital, England, UK.

SUBJECTS

Twenty-three patients with tuberculosis of the head and neck diagnosed by culture of specimens obtained by fine needle biopsy (n = 8) or by open biopsy of the lumps in the neck (n = 15) who presented between 1990 and 1993.

MAIN OUTCOME MEASURES

methods of diagnosis and management.

RESULTS

thirteen of the 23 patients (57%) presented with either a fluctuant mass or a discharging sinus in the neck. Nine (39%) had uncomplicated enlarged lymph nodes and 12 (55%) had systemic symptoms. The supraclavicular region was the most common site (n = 11) and 8 of these 11 had abnormalities in the chest radiograph. In 3 patients the disease was resistant to treatment with standard antituberculous treatment.

CONCLUSIONS

atypical mycobacterial lymphadenitis is usually resistant to standard antituberculous treatment, so it is essential to obtain a microbiological diagnosis. Excision is usually the treatment of choice for such patients.

摘要

目的

回顾头颈部结核的临床特征及治疗方法,并确定有助于诊断的特征。

设计

回顾性研究。

地点

英国英格兰的教学医院。

研究对象

1990年至1993年间,23名头颈部结核患者,其中8例通过细针穿刺活检获取标本培养确诊,15例通过颈部肿块开放活检确诊。

主要观察指标

诊断和治疗方法。

结果

23例患者中,13例(57%)颈部出现波动感肿块或窦道排脓。9例(39%)有单纯性淋巴结肿大,12例(55%)有全身症状。锁骨上区域是最常见部位(11例),这11例中有8例胸部X线片异常。3例患者对标准抗结核治疗耐药。

结论

非典型分枝杆菌淋巴结炎通常对标准抗结核治疗耐药,因此进行微生物学诊断至关重要。此类患者通常首选手术切除治疗。

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