Chin P K, Cuzzani O E, Gimbel H V, Sun R
Gimbel Eye Centre, Calgary, Alta.
Can J Ophthalmol. 1996 Dec;31(7):362-5.
To compare the effect of tropicamide alone and tropicamide-phenylephrine on anterior chamber flare and cell measurements obtained with a laser flare-cell meter.
Prospective study.
Gimbel Eye Centre, Calgary.
Twenty white subjects (10 with blue irides and 10 with brown irides) aged 24 to 45 (mean 30.2) years without any known systemic or ocular disease.
Laser flare-cell measurements were obtained 30 minutes after pupillary dilation with 1% tropicamide in one eye and a combination drop of 0.8% tropicamide and 5% phenylephrine in the other eye. The average of five readings was taken for each eye.
Flare and cell measurements.
There was no statistically significant difference in flare photon count or cell count between the eyes dilated with tropicamide and those dilated with tropicamide-phenylephrine. In addition, iris colour was not found to have a significant effect on flare and cell measurements.
Our results suggest that pupillary dilation for laser flare-cell measurements can be done with either mydriatic agent in healthy white subjects of any eye colour without significant effects on the measurements. Further study is needed to determine whether the same is true in older subjects.
比较单独使用托吡卡胺和托吡卡胺 - 去氧肾上腺素对使用激光闪光细胞仪测量前房闪光和细胞计数的影响。
前瞻性研究。
卡尔加里的金贝尔眼科中心。
20名白人受试者（10名蓝虹膜和10名棕虹膜），年龄24至45岁（平均30.2岁），无任何已知的全身或眼部疾病。
一只眼睛用1%托吡卡胺散瞳30分钟后进行激光闪光细胞测量，另一只眼睛用0.8%托吡卡胺和5%去氧肾上腺素的复方滴眼液散瞳。每只眼睛取五次读数的平均值。
闪光和细胞计数。
用托吡卡胺散瞳的眼睛和用托吡卡胺 - 去氧肾上腺素散瞳的眼睛之间，闪光光子计数或细胞计数没有统计学上的显著差异。此外，未发现虹膜颜色对闪光和细胞测量有显著影响。
我们的结果表明，在任何眼色的健康白人受试者中，使用任何一种散瞳剂进行激光闪光细胞测量的散瞳操作，对测量结果均无显著影响。需要进一步研究以确定在老年受试者中是否也是如此。
