Mackie F E, Hodson E M, Roy L P, Knight J F
Centre for Kidney Research, Royal Alexandra Hospital for Children, Sydney, Australia.
Pediatr Nephrol. 1996 Dec;10(6):756-8. doi: 10.1007/s004670050210.
Neonatal Bartter syndrome differs from the classical Bartter syndrome in the occurrence of antenatal presentation with polyhydramnios. Nephrocalcinosis and severe growth retardation are common sequelae. Indomethacin has been reported to improve linear growth, but its use in the early newborn period has been infrequently described. In this paper we report normal growth and development and the absence of nephrocalcinosis in an infant now aged 19 months with neonatal Bartter syndrome treated from day 3 of life with indomethacin. With early diagnosis and treatment with indomethacin plus adequate water, calories, and sodium, normal growth can be achieved and nephrocalcinosis may be prevented in children with neonatal Bartter syndrome.
新生儿巴特综合征与经典巴特综合征不同，前者常于产前出现羊水过多。肾钙质沉着症和严重生长发育迟缓是常见的后遗症。据报道，吲哚美辛可改善线性生长，但在新生儿早期使用吲哚美辛的情况鲜有描述。在本文中，我们报告了一名19个月大的患有新生儿巴特综合征的婴儿，自出生第3天起接受吲哚美辛治疗，其生长发育正常且未出现肾钙质沉着症。对于新生儿巴特综合征患儿，通过早期诊断并使用吲哚美辛治疗，同时补充足够的水分、热量和钠，可实现正常生长并预防肾钙质沉着症。
