矢车菊素 3 - O - β - D - 葡萄糖苷与自由基引发剂的氧化产物。

Oxidation products of cyanidin 3-O-beta-D-glucoside with a free radical initiator.

作者信息

Tsuda T, Ohshima K, Kawakishi S, Osawa T

机构信息

Tokaigakuen Women's College, Nagoya, Japan.

出版信息

Lipids. 1996 Dec;31(12):1259-63. doi: 10.1007/BF02587910.

DOI:10.1007/BF02587910

PMID:8972458

Abstract

Recently, we have reported that anthocyanins show strong antioxidative activity, but no attention has been paid to anthocyanins from the viewpoint of the reaction mechanism of alkylperoxyl radicals; therefore, we investigated the reaction products of antioxidative anthocyanins (cyanidin 3-O-beta-D-glucoside). Cyanidin 3-O-beta-D-glucoside was reacted with 2,2'-azobis(2,4-dimet hylvaleronitrile) to generate the alkylperoxyl radicals, and the reaction products were isolated by high-performance liquid chromatography. The products were identified as 4,6-dihydroxy-2-O-beta-D-glucosyl-3-oxo-2,3-dihydroben-zofuran+ ++ and protocatechuic acid. Based on reaction products, the antioxidative mechanism of cyanidin 3-O-beta-D-glucoside may be different from that of alpha-tocopherol; cyanidin 3-O-beta-D-glucoside would produce another radical scavenger, as it would break down the structure and scavenge the radicals.

摘要

最近，我们报道了花青素具有很强的抗氧化活性，但从烷基过氧自由基的反应机制角度来看，花青素尚未受到关注；因此，我们研究了抗氧化花青素（矢车菊素 3 - O - β - D - 葡萄糖苷）的反应产物。使矢车菊素 3 - O - β - D - 葡萄糖苷与 2,2'-偶氮二(2,4 - 二甲基戊腈)反应以生成烷基过氧自由基，反应产物通过高效液相色谱法分离。产物被鉴定为 4,6 - 二羟基 - 2 - O - β - D - 葡萄糖基 - 3 - 氧代 - 2,3 - 二氢苯并呋喃和原儿茶酸。基于反应产物，矢车菊素 3 - O - β - D - 葡萄糖苷的抗氧化机制可能与α - 生育酚不同；矢车菊素 3 - O - β - D - 葡萄糖苷会产生另一种自由基清除剂，因为它会破坏结构并清除自由基。