Kõljalg S, Vuopio-Varkila J, Lyytikäinen O, Mikelsaar M, Wadström T
Institute of Microbiology, Tartu University, Estonia.
APMIS. 1996 Sep;104(9):659-65.
Cell surface properties of 78 strains of Acinetobacter baumannii of different origin (lower respiratory tract, wound, blood and environment) were investigated. The bacterial adhesion to collagen, fibronectin, fibrinogen and vitronectin was detected by particle agglutination assays. Salt aggregation tests were used to determine the cell surface hydrophobicity of isolated A. baumannii strains. We found that A. baumannii strains originating from patients with wound infection and bacteraemia showed significantly lower aggregative properties compared to respiratory and environmental strains. Electron microscopic investigations revealed more fimbriated bacterial cells among the highly aggregative A. baumannii strains. This study demonstrates that the investigated A. baumannii strains can be divided into two different groups according to their cell surface properties and source of isolation, whereas the majority of strains, from the lower respiratory tract and the hospital environment expressed strong adhesive properties.
对78株不同来源（下呼吸道、伤口、血液和环境）的鲍曼不动杆菌的细胞表面特性进行了研究。通过颗粒凝集试验检测细菌对胶原蛋白、纤连蛋白、纤维蛋白原和玻连蛋白的黏附。采用盐凝集试验测定分离出的鲍曼不动杆菌菌株的细胞表面疏水性。我们发现，与呼吸道和环境来源的菌株相比，源自伤口感染患者和菌血症患者的鲍曼不动杆菌菌株的凝集特性明显较低。电子显微镜研究显示，在高度凝集的鲍曼不动杆菌菌株中，有更多带菌毛的细菌细胞。本研究表明，根据所研究的鲍曼不动杆菌菌株的细胞表面特性和分离来源可将其分为两个不同的组，而来自下呼吸道和医院环境的大多数菌株表现出较强的黏附特性。
