Funaki M, Ohno T, Dekio S, Jidoi J, Nakagawa C, Kin S, Tamura K
Department of Dermatology, Shimane Medical University, Izumo, Japan.
J Dermatol. 1996 Oct;23(10):703-7. doi: 10.1111/j.1346-8138.1996.tb02684.x.
In a male Japanese patient, prurigo nodularis (PN) appeared in association with gastric cancer. The cutaneous pruriginous lesions dramatically improved soon after total gastrectomy without any treatment for the skin lesions. Peripheral eosinophilia seen before the operation also rapidly disappeared. These data suggest that some cytokines involved in gastric cancer might have played an important role in the development of PN in our patient.
在一名日本男性患者中,结节性痒疹(PN)与胃癌相关出现。在全胃切除术后,皮肤瘙痒性病变在未对皮肤病变进行任何治疗的情况下很快显著改善。术前出现的外周嗜酸性粒细胞增多也迅速消失。这些数据表明,参与胃癌的某些细胞因子可能在我们这位患者的PN发病过程中发挥了重要作用。