TCFL4：一个位于17q21.1的基因，编码一种假定的碱性螺旋-环-螺旋亮氨酸拉链转录因子。
TCFL4: a gene at 17q21.1 encoding a putative basic helix-loop-helix leucine-zipper transcription factor.
作者信息
Bjerknes M, Cheng H
机构信息
Department of Anatomy and Cell Biology, University of Toronto, Ont., Canada.
出版信息
Gene. 1996 Nov 28;181(1-2):7-11. doi: 10.1016/s0378-1119(96)00376-9.
TCFL4 (transcription factor like 4) is the HGMW-approved symbol for the gene of a widely expressed putative basic helix-loop-helix leucine-zipper (bHLH-zip) transcription factor which is located 3' to HSD17B1 (17-beta-hydroxysteroid dehydrogenase gene) at 17q21.1, centromeric to the BRCA1 (a gene implicated in familial breast cancer) locus. We report the human gene structure and the murine cDNA sequence of two variants, about 1.5 and 2.2 kb in size. The deduced protein is highly conserved between mouse and man.
TCFL4（类转录因子4）是一个经HGMW批准的基因符号，该基因编码一种广泛表达的假定碱性螺旋-环-螺旋亮氨酸拉链（bHLH-zip）转录因子，位于17q21.1上HSD17B1（17-β-羟基类固醇脱氢酶基因）的3'端，在BRCA1（一个与家族性乳腺癌相关的基因）位点的着丝粒侧。我们报道了两种大小分别约为1.5 kb和2.2 kb的变体的人类基因结构和小鼠cDNA序列。推导的蛋白质在小鼠和人类之间高度保守。
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