雌酮水溶液对鸡胚大脑半球糖原的消耗作用。
The glycogen-depleting effect of aqueous estrone on the cerebral hemispheres of the chick embryo.
作者信息
Delphia J M, Negulesco J A
出版信息
Res Commun Chem Pathol Pharmacol. 1977 Jul;17(3):539-42.
PMID:897343
Abstract
Aqueous estrone (10 to 50 pigrams/egg) was injected into the albumen of the 13 day chick embryo. The control solution and estrone carrier was 0.1 ml bacteriostatic saline. The KOH-alcohol-Anthrone colorimetric method was used to determine glycogen. 20 or more pigrams estrone/egg lowered the mean cerebral glycogen significantly (P less than 0.01) after 24 hours duration in a non-dosage-dependent manner. The glycolytic effect was demonstrated by the 20.0 pigram dosage after 120 hours duration.
摘要
将水合雌酮（10至50微克/枚鸡蛋）注射到13日龄鸡胚的蛋白中。对照溶液和雌酮载体为0.1毫升抑菌生理盐水。采用氢氧化钾 - 乙醇 - 蒽酮比色法测定糖原。在24小时后，20微克或更多微克雌酮/枚鸡蛋以非剂量依赖方式显著降低大脑平均糖原含量（P小于0.01）。在120小时后，20.0微克剂量显示出糖酵解作用。
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