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乙醇对鸡胚大脑糖原水平的影响。

The effect of ethanol on cerebral glycogen levels in the chick embryo.

作者信息

Delphia J M, Negulesco J A, Finan E

出版信息

Res Commun Chem Pathol Pharmacol. 1978 Aug;21(2):347-50.

PMID:694231
Abstract

Ethanol (10 to 50 micro-liters/egg) was injected into the albumen of the 13 day chick embryo. The control solution and ethanol carrier was bacteriostatic saline (0.1 ml). The KOH-alcohol-Anthrone colorimetric method was used for glycogen determination. Ethanol at 20 or 30 mul/egg lowered the mean cerebral glycogen (p less than 0.05). Higher dosages elevated cerebral glycogen over the same time period (p less than 0.05). The glycogen-depleting effect of 20 mul/egg and the glycogen increasing effect of 40 mul/egg were maintained through 168 hours of ethanol exposure (20 days incubation).

摘要

将乙醇(10至50微升/枚鸡蛋)注入13日龄鸡胚的蛋白中。对照溶液和乙醇载体为抑菌生理盐水(0.1毫升)。采用氢氧化钾-乙醇-蒽酮比色法测定糖原。20或30微升/枚鸡蛋的乙醇降低了大脑糖原的平均值(p<0.05)。在同一时间段内,较高剂量可提高大脑糖原含量(p<0.05)。在乙醇暴露168小时(孵化20天)的过程中,20微升/枚鸡蛋的糖原消耗作用和40微升/枚鸡蛋的糖原增加作用持续存在。

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