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妊娠对非转移性乳腺癌的影响:一项病例对照研究。

Impact of pregnancy on non-metastatic breast cancer: a case control study.

作者信息

Ezzat A, Raja M A, Berry J, Zwaan F E, Jamshed A, Rhydderch D, Rostom A, Bazarbashi S

机构信息

King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia.

出版信息

Clin Oncol (R Coll Radiol). 1996;8(6):367-70. doi: 10.1016/s0936-6555(96)80081-1.

DOI:10.1016/s0936-6555(96)80081-1
PMID:8973852
Abstract

The diagnosis of breast cancer during pregnancy remains uncommon and therefore leads to non-standardized management. We reviewed retrospectively 28 such women treated at this centre and compared them with age and stage matched controls. Differences in management and outcome were analysed for statistical significance. There was no significant difference in overall survival (P = 0.86) and relapse-free survival (P = 0.48) between the two groups. Chemotherapy after the first trimester of pregnancy carried no significant morbidity. Pregnancy does not appear to be an adverse prognostic factor for breast cancer.

摘要

孕期乳腺癌的诊断仍然不常见,因此导致管理不规范。我们回顾性分析了本中心治疗的28例此类患者,并将她们与年龄和分期匹配的对照组进行比较。分析管理和结果的差异,以确定统计学意义。两组之间的总生存率(P = 0.86)和无复发生存率(P = 0.48)没有显著差异。妊娠前三个月后的化疗没有显著的发病率。妊娠似乎不是乳腺癌的不良预后因素。

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