Otieno L H, Darji N, Onyango P
Acta Trop. 1976;33(2):143-50.
Classically, infective development of Trypanosoma (Trypanozoon) brucei in tsetse flies is thought to take the route crop-midgut-hindgut proventriculus-hypopharynx-salivary gland, where the parasites reach their infective phase. It has been shown experimentally that T. (T.) brucei is capable of developing up to the infective stage in G. morsitans following inoculation of bloodstream form trypanosomes into the haemocoel. The rabbit on which flies were maintained became infected 18 days after exposure to the bite of experimentally inoculated flies. The possibility that T. (T.) brucei may be transmitted cyclically from tsetse flies to a mammalian host without necessarily following the classical, prescribed route is discussed. Apart from the normal longitudinal binary fission, various modes of multiplication were observed among trypanosomes in the haemocoel, modes which have not been observed previously in the tsetse fly.
传统上，布氏锥虫（布氏锥虫亚属）在采采蝇体内的感染性发育过程被认为是沿着作物-中肠-后肠-前胃-下咽-唾液腺这一路径进行的，寄生虫在这个过程中进入感染阶段。实验表明，将血流形式的锥虫接种到冈比亚采采蝇的血腔后，布氏锥虫（布氏锥虫亚属）能够发育到感染阶段。在接触经实验接种的采采蝇叮咬18天后，饲养采采蝇所用的兔子被感染。文中讨论了布氏锥虫（布氏锥虫亚属）可能不一定要遵循传统规定的途径，而是以循环方式从采采蝇传播到哺乳动物宿主的可能性。除了正常的纵向二分裂外，在血腔中的锥虫之间还观察到了各种增殖模式，这些模式以前在采采蝇中未曾见过。
