Platelet transfusion therapy.

Although platelet transfusion is a vital part of modern hemotherapy, many related issues are unresolved. The most appropriate trigger point of transfusion and the clinical utility of prophylactic transfusion are still debated, but the importance of patient-specific transfusion decisions is clear. Leukocyte reduction and single donor platelets may have important roles in avoiding complications, but more data are needed. Establishment of a standardized protocol for managing patients receiving ongoing platelet transfusions may facilitate application of special techniques and the use of specially chosen units that provide better platelet support for thrombocytopenic patients.