Savchenko L V, Dzuban E M, Luk'ianchuk V D
Eksp Klin Farmakol. 1996 Mar-Apr;59(2):53-5.
The influence of calcium channel blockers on pro-oxidant-antioxidant balance in hypoxic syndrome is studied. Both verapamil and cinnarizine were shown to prevent formation and accumulation of lipid peroxidation products in the tissues and normalize the basic components of the system of antioxidant protection. Probable mechanisms of the antioxidant action of the calcium channel blockers are discussed.
研究了钙通道阻滞剂对缺氧综合征中促氧化剂 - 抗氧化剂平衡的影响。结果表明，维拉帕米和桂利嗪均可防止组织中脂质过氧化产物的形成和积累，并使抗氧化保护系统的基本成分恢复正常。文中还讨论了钙通道阻滞剂抗氧化作用的可能机制。
