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[系统性暴露于振动的家兔脑结构电活动变化与组织呼吸指标的相关性]

[Correlation of changes in the electrical activity and indices of tissue respiration of brain structures in rabbits exposed systematically to vibration].

作者信息

Minasian S M, Baklavadzhian O G, Oganisian A O, Andriasian A D

机构信息

Erevan State University.

出版信息

Aviakosm Ekolog Med. 1996;30(5):36-40.

PMID:8974597
Abstract

The electrical activity and tissue respiration of the cortex and subcortex (posterior hypothalamic nucleus, Deiters' vestibular nucleus) have been studied in the rabbits during 3-month exposure to vibration (60H2, for 3h daily). On days 15-30 of exposure to vibration the electrocorticogram demonstrated the prevalence of alfa-waves whereas in the subcortex the teta-waves were dominated. On long-term vibration exposure (2-3 months), the synchronized slow waves were recorded on the EEG. Comparison of a changed electrical activity of the various structures of the brain with the level of oxidizing metabolism enabled us to reveal their definite interrelationship. In the early stage of vibration exposure there has been observed an increased absorption of oxygen by the brain structures and the elevated activity of succinate dehydrogenase. The prolonged vibration resulted in a decreased level of tissue respiration and activity of respiratory enzyme. Under vibration exposure there has been revealed a statistically significant direct relationship between the content of absorbed oxygen, activity of succinate dehydrogenase and the shifts in the electrical activity of cerebral structures.

摘要

在兔子暴露于振动(60Hz,每天3小时)3个月的过程中,对其大脑皮层和皮层下结构(下丘脑后核、德伊特氏前庭核)的电活动和组织呼吸进行了研究。在暴露于振动的第15至30天,脑电图显示α波占优势,而在皮层下则以θ波为主。在长期振动暴露(2至3个月)时,脑电图记录到同步慢波。将大脑不同结构电活动的变化与氧化代谢水平进行比较,使我们能够揭示它们之间明确的相互关系。在振动暴露的早期阶段,观察到脑结构对氧气的吸收增加以及琥珀酸脱氢酶的活性升高。长时间的振动导致组织呼吸水平和呼吸酶活性降低。在振动暴露下,发现吸收的氧气含量、琥珀酸脱氢酶的活性与脑结构电活动的变化之间存在统计学上显著的直接关系。

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Aviakosm Ekolog Med. 1996;30(5):36-40.
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