Beck K H, Niese A, Matic G B, Wisnieswski U, Ahnert K, Beeser H
Transfusionsmedizin, Universitätsklinik Freiburg, Deutschland.
Beitr Infusionsther Transfusionsmed. 1996;33:206-9.
Tolerance of autologous blood donation was investigated in a patient group aged between 66 and 75 years (median = 70 years). Autologous blood donors between 18 and 65 years (median = 51 years) served as a control. A total of 38 patients were examined. Only blood donors which did not exceed ASA criteria II were accepted. Blood donation was performed weekly with a daily ferrum intake of 200 mg. Patients were divided into two groups with and without volume replacement, respectively. The parameters investigated were: blood pressure and pulse before and after the first and second autologous blood donation, circulatory response during 24 h after blood donation, and hemoglobin concentration before the first, second, and third donation. Regarding pulse and blood pressure, there was no statistical difference between the elder and younger patient group. Hemoglobin reduction from the first to the second donation was 1.1 g/dl in both groups and from the second to the third donation 1.1 g/dl in the younger group and 1.2 g/dl in the elder patient group. Again, no significant difference between both groups could be shown. None of the 38 patients showed negative side effects regarding the circulatory response during a time period of 24 h after blood donation.
对年龄在66至75岁（中位数 = 70岁）的患者组进行了自体献血耐受性的研究。年龄在18至65岁（中位数 = 51岁）的自体献血者作为对照。共检查了38名患者。仅接受不超过美国麻醉医师协会（ASA）标准II级的献血者。每周进行一次献血，每日铁摄入量为200毫克。患者分别分为有和没有容量替代的两组。所研究的参数包括：第一次和第二次自体献血前后的血压和脉搏、献血后24小时内的循环反应以及第一次、第二次和第三次献血前的血红蛋白浓度。在脉搏和血压方面，老年患者组和年轻患者组之间没有统计学差异。两组中从第一次到第二次献血血红蛋白降低均为1.1克/分升，年轻组从第二次到第三次献血血红蛋白降低1.1克/分升，老年患者组为1.2克/分升。同样，两组之间未显示出显著差异。38名患者中没有一人在献血后24小时内的循环反应方面表现出负面副作用。
