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使用2-[¹⁸F]氟脱氧-D-葡萄糖正电子发射断层扫描(FDG-PET)检测多灶性乳腺癌

[Detection of multi-focal breast carcinoma using 2[18F] fluoro-deoxy-D-glucose positron emission tomography (FDG-PET)].

作者信息

Scharl A, Scheidhauer K, Pietrzyk U, Göhring U J, Schomäcker K

机构信息

Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe, Universität zu Köln.

出版信息

Geburtshilfe Frauenheilkd. 1996 Aug;56(8):434-7. doi: 10.1055/s-2007-1023260.

DOI:10.1055/s-2007-1023260
PMID:8974899
Abstract

The elevated rate of glycolysis in malignomas compared to normal tissues can be visualised by positron-emission-tomography (PET) using 2[18F]fluoro-deoxy-D-Glucose (FDG). Based on the case of a 38-year old woman with multifocal carcinoma of the right breast (pT1 c pN0 M0, G2) as a vehicle, we describe a FDG-PET procedure which is comparable to established methods of nuclear medicine (e.g. bone scan) with regard to patient's burden and time consumption and could be used on a routine basis. This technique allowed correct assessment of suspicious breast findings and visualised multifocal growth of a tumour which was judged to be a unifocal breast cancer by conventional methods of clinical examination, mammography and ultrasound.

摘要

与正常组织相比,恶性肿瘤中糖酵解速率升高的情况可通过正电子发射断层扫描(PET)利用2-[18F]氟-脱氧-D-葡萄糖(FDG)进行可视化。以一名38岁患有右乳多灶性癌(pT1 c pN0 M0,G2)的女性病例为载体,我们描述了一种FDG-PET检查程序,该程序在患者负担和时间消耗方面与核医学的既定方法(如骨扫描)相当,并且可以常规使用。这项技术能够正确评估可疑的乳腺病变,并显示出肿瘤的多灶性生长,而通过传统的临床检查、乳腺X线摄影和超声检查方法,该肿瘤被判定为单灶性乳腺癌。

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