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[关于肢体骨旁脂肪瘤]

[On parosteal lipomas of the limbs].

作者信息

Stagno d'Alcontres F, Pardo A, Stracuzzi G

机构信息

Cattedra di Chirurgia Plastica e Ricostruttiva, Università degli Studi, Catania.

出版信息

Minerva Chir. 1996 Jul-Aug;51(7-8):607-16.

PMID:8975166
Abstract

Among the benign neoplasias of mesenchymal origin, parosteal lipomas represent a relatively rare occurrence. They are deep seated (subfascial) lipomas which during the course of their slow growth become adherent to the periosteum. The parosteal lipoma is not dissimilar to the so-called common or superficial lipoma both in terms of its macroscopic appearance, since this neoplasia has no capsule which separates it from surrounding tissue and likewise enables an easy enucleation owing to the presence of a cleavage plane, and in terms of its microscopic appearance since it is made up of mature adipose cells. Moreover, comparative cytogenic tests have revealed chromosomic alterations common to both the superficial and parosteal lipoma. The peculiarity of the parosteal lipoma lies in its clinical evolution which depends on the original site; it is in fact most often described in relation to bone segments of the limbs where it may lead to the compression of the vasculonervous axes. In particular, parosteal lipoma of the forearm, especially if localised in the upper third, represents a separate clinical entity given that, during the course of its growth, it may cause the compression of the posterior interosseous nerve and the surface (sensitive) branch of the radial nerve. This occurrence, which is observed in approximately half of all cases, must be taken into consideration and should lead to the decision to operate in order to prevent compressive sequelae involving nervous axes. After reviewing the literature on the subject, the authors report their experience of four recent cases and evaluate the anatomical, clinical, diagnostic and therapeutic aspects of parosteal lipoma.

摘要

在间叶组织来源的良性肿瘤中,骨旁脂肪瘤相对少见。它们是深部(筋膜下)脂肪瘤,在缓慢生长过程中会与骨膜粘连。骨旁脂肪瘤在宏观外观上与所谓的普通或浅表脂肪瘤并无不同,因为这种肿瘤没有将其与周围组织分隔开的包膜,同样由于存在分离平面而易于摘除;在微观外观上也相似,因为它由成熟的脂肪细胞组成。此外,比较细胞遗传学检测发现浅表脂肪瘤和骨旁脂肪瘤都存在染色体改变。骨旁脂肪瘤的特殊性在于其临床演变取决于原发部位;事实上,它最常与四肢的骨段相关,可能导致血管神经轴受压。特别是前臂的骨旁脂肪瘤,尤其是位于上三分之一处时,代表一种独立的临床实体,因为在其生长过程中,可能会压迫骨间后神经和桡神经的皮(感觉)支。这种情况在大约一半的病例中会出现,必须予以考虑,并应决定进行手术以防止涉及神经轴的压迫后遗症。在回顾了关于该主题的文献后,作者报告了他们最近四例病例的经验,并评估了骨旁脂肪瘤的解剖学、临床、诊断和治疗方面。

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