Ratajczak B, Wierzba J, Irga N, Czarniak P, Kosiak W, Samet A, Chabior M
I Klinika Chorób Dzieci Akademii Medycznej w Gdańsku.
Pediatr Pol. 1996 Apr;71(4):331-7.
The authors present the clinical course of 8 cases of fungal infection of the urinary tract in newborns. Three of the investigated children were premature or with intrauterine hypotrophy, a congenital defect of the urinary tract was detected in one child. In 5 cases the fungal infection followed bacterial septicaemia. Two of the 8 children required peritoneal dialysis, another two required insertion of intravenous catheters for parenteral feeding, and four required bladder catheterisation. The diagnosis of fungal urinary tract infection was established on the basis of urine culture, the presence of specific serum anti-candida antibodies and results of ultrasonographic examination (vs). In 7 of 8 cases the possibility of fungal infection was suggested by US examination. Seven children were treated with fluconazole combined with 5-fluorocytosine, one was treated with fluconazole. Pyelostomy was performed, in two of the patients all of them received supportive treatment. Our clinical observations point to the necessity of prophylaxis in case of predisposing factors to fungal infection and the use of abdominal ultrasonography for detection of early stages of fungal urinary tract infection.
作者介绍了8例新生儿真菌性尿路感染的临床病程。其中3例受调查儿童为早产儿或有宫内发育迟缓，1例儿童检测出先天性尿路缺陷。5例真菌感染继发于细菌性败血症。8名儿童中有2名需要腹膜透析，另外2名需要插入静脉导管进行肠外营养，4名需要膀胱插管。真菌性尿路感染的诊断基于尿培养、特异性血清抗念珠菌抗体的存在以及超声检查（vs）结果。8例中有7例超声检查提示有真菌感染的可能。7名儿童接受氟康唑联合5-氟胞嘧啶治疗，1名接受氟康唑治疗。进行了肾盂造口术，所有患者中有2名接受了支持治疗。我们的临床观察表明，对于有真菌感染易感因素的情况有必要进行预防，并使用腹部超声检查来检测真菌性尿路感染的早期阶段。
