Tvedt B, Krogstad J M, Berstad J
Sunnaas sykehus, Nesoddtangen.
Tidsskr Nor Laegeforen. 1996 Oct 20;116(25):3005-8.
Four patients with hypoxic brain damage caused by carbon monoxide poisoning are described. Three of these had attempted suicide with car exhaust fumes. Two patients had visual agnosia due to lesions in the parieto-occipital cortex. Three patients had temporary Parkinsonian symptoms. In two of these patients CT and MRI showed lesions in the globus pallidus. They also showed reduced initiative, and in one patient this was combined with minor tics and obsessive symptoms. One patient had impaired memory as the only symptom. The patient with the longest lasting exposure developed delayed sequelae; three weeks after the poisoning he became apathetic and confused, with failing memory, Parkinsonian symptoms, and urinary and faecal incontinence. MRI showed demyelination in the periventricular white matter. His condition started to improve two months after the accident.
本文描述了4例因一氧化碳中毒导致缺氧性脑损伤的患者。其中3例曾试图吸入汽车尾气自杀。2例患者因顶枕叶皮质病变出现视觉失认症。3例患者出现了短暂的帕金森症状。其中2例患者的CT和MRI显示苍白球有病变。他们还表现出主动性降低，其中1例患者还伴有轻微抽搐和强迫症状。1例患者仅出现记忆力受损这一症状。中毒时间最长的患者出现了迟发性后遗症；中毒三周后，他变得冷漠、困惑，记忆力减退，出现帕金森症状，大小便失禁。MRI显示脑室周围白质脱髓鞘。事故发生两个月后，他的病情开始好转。
