Suppr超能文献

[门静脉高压症——问题介绍]

[Portal hypertension--introduction to the problem].

作者信息

Brodanová M

机构信息

I. interní klinika 1. LF UK a VFN, Praha.

出版信息

Vnitr Lek. 1996 Oct;42(10):696-9.

PMID:8975461
Abstract

Portal hypertension is a condition with a permanently raised pressure in the portal area. The most frequent cause is restricted blood flow through some part of the circulation. Depending on the site of obstruction, we classify portal hypertension into prohepatic, hepatic and posthepatic. In adult age the most frequent form is the hepatic one associated with cirrhosis of the liver, in childhood prehepatic hypertension associated with thrombosis of the porta. The significance of portal hypertension is due in particular to its sequelaes. Among the most serious ones is the development of a collateral circulation with subsequent gastroesophageal varicosities. The latter involve the risk of rupture and massive haemorrhage into the gastrointestinal tract. The patient develops posthaemorrhagic shock. The author mentions the most important metabolic and cellular changes caused by shock. The importance of complications is emphasised. Haemorrhage is frequently followed by hepatic failure, which even nowadays is usually fatal. The author mentions also the risks of hypersplenism and emphasizes their participation in haemorrhage. In the introduction the author points out why wo much attention should be paid so portal hypertension and procedures influencing it.

摘要

门静脉高压是一种门静脉区域压力持续升高的病症。最常见的病因是血液循环某些部位的血流受限。根据梗阻部位,我们将门静脉高压分为肝前性、肝性和肝后性。在成年人中,最常见的类型是与肝硬化相关的肝性门静脉高压,在儿童中则是与门静脉血栓形成相关的肝前性高血压。门静脉高压的重要性尤其在于其并发症。其中最严重的是侧支循环的形成以及随后的胃食管静脉曲张。后者存在破裂和胃肠道大量出血的风险。患者会发生出血后休克。作者提到了休克引起的最重要的代谢和细胞变化。强调了并发症的重要性。出血后常常继发肝衰竭,即使在当今,肝衰竭通常也是致命性的。作者还提到了脾功能亢进的风险,并强调了它们在出血中的作用。在引言中,作者指出了为何应如此重视门静脉高压及其相关治疗措施。

相似文献

3
7
8
Modern management of portal hypertension.门静脉高压症的现代管理
Intern Med J. 2005 Jan;35(1):45-9. doi: 10.1111/j.1445-5994.2004.00739.x.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验