（D）-青霉胺治疗系统性硬化症（硬皮病）。对营养性毛细血管循环的影响。
(D)-penicillamine treatment in systemic sclerosis (scleroderma). Effect on nutritional capillary circulation.
作者信息
Mellstedt H, Fagrell B, Holm G, Björkholm M
出版信息
Scand J Rheumatol. 1977;6(2):92-6. doi: 10.3109/03009747709095427.
PMID:897590
Abstract
Four patients with systemic sclerosis (scleroderma) were treated with (D)-penicillamine (1.2-1.8 g/d) for 18-60 months. All patients improved. Vital capillary microscopy demonstrated that the number of visible skin capillaries increased during therapy, thus indicating a more efficient nutritional circulation.
摘要
4例系统性硬化症（硬皮病）患者接受青霉胺（D-青霉胺）治疗（1.2-1.8g/天），疗程为18-60个月。所有患者均有改善。动态毛细血管显微镜检查显示，治疗期间可见皮肤毛细血管数量增加，表明营养循环效率更高。
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