Suominen E, Kinnunen J
Department of Plastic Surgery, Töölö Hospital, Helsinki University Central Hospital, Finland.
Scand J Plast Reconstr Surg Hand Surg. 1996 Dec;30(4):281-9. doi: 10.3109/02844319609056406.
Non-vascularised bone grafts that are used for reconstruction of skeletal deformities of the face after trauma or tumour surgery are prone to resorption. The outcome may, therefore, not be what was expected. Bone was reconstructed with bioactive glass S53P4 granules and plates at 36 sites in 13 patients. The behaviour of the material was compared with that of bone grafts at 16 sites in the same patients. Bioactive glass granules were used in facial bone defects in subperiosteal pockets and to obliterate frontal sinuses, whereas bioactive glass plates were used mostly in orbital wall reconstruction. Clinical examination, middle face radiographs, and computed tomograms (CT) showed that the material was well tolerated. A third of the glass granules and a quarter of the membranous bone grafts that were fixed with miniplates retained their original size. The glass plates did not change in size. Bone contact to the host bone was found more often with the bioactive glass plates than with the bioactive glass granules or the bone grafts. Both the glass plates and the bone grafts retained their density, but there was a reduction in density of the glass granules. The clinical outcome showed no relapses after one year's follow up. No further operations were needed because of the material used.
用于创伤或肿瘤手术后面部骨骼畸形重建的非血管化骨移植容易发生吸收。因此，结果可能不尽如人意。在13例患者的36个部位使用生物活性玻璃S53P4颗粒和板材进行骨重建。将该材料的表现与同一患者16个部位的骨移植表现进行比较。生物活性玻璃颗粒用于骨膜下袋的面部骨缺损和闭塞额窦，而生物活性玻璃板材主要用于眶壁重建。临床检查、中面部X线片和计算机断层扫描（CT）显示该材料耐受性良好。三分之一的玻璃颗粒和四分之一用微型钢板固定的膜性骨移植保留了其原始大小。玻璃板材大小未改变。与生物活性玻璃颗粒或骨移植相比，生物活性玻璃板材与宿主骨的骨接触更常见。玻璃板材和骨移植均保持其密度，但玻璃颗粒的密度有所降低。临床结果显示，随访一年后无复发。由于使用了该材料，无需进一步手术。
