Weidner W, Schroeder-Printzen I, Weiske W H, Vosshenrich R
Department of Urology, University of Giessen, Germany.
J Urol. 1997 Jan;157(1):325-8. doi: 10.1016/s0022-5347(01)65370-9.
We obtained an objective evaluation of erectile function in patients with Peyronie's disease.
Sexual dysfunction was analyzed in 222 patients with Peyronie's disease without previous local plaque therapy using a standardized protocol.
Of the 222 patients 70 (31.5%) complained of not being able to perform intercourse. In 4 men (1.8%) standardized diagnostic procedure demonstrated only a severe angulation making coitus impossible, and in 3 men (1.4%) intercourse became unsatisfactory due to pain. Seven men (3.1%) reported distal penile flaccidity, including 4 in whom dynamic pharmacocavernosometry and pharmacocavernosography revealed veno-occlusive dysfunction. Of 56 men who complained of a complete loss of erection 51 did not respond to intracavernous pharmacological injection with prostaglandin E1, and 27 (48.2%) had abnormal arterial blood flow as shown by duplex sonography of the cavernous arteries, 47 (83.9%) had evidence of veno-occlusive dysfunction based on cavernosometric criteria and 33 (58.9%) also had cavernosographic evidence of the condition. Plaque associated venous drainage was evident in 15 of the 56 impotent patients (26.8%), equivalent to 45.5% of all cases with abnormal cavernosographic findings.
Sexual dysfunction was evaluable in 31.5% of patients, and the main cause of impotence and loss of erection was veno-occlusive dysfunction.
我们对佩罗尼氏病患者的勃起功能进行了客观评估。
采用标准化方案对222例未曾接受过局部斑块治疗的佩罗尼氏病患者的性功能障碍进行了分析。
222例患者中，70例（31.5%）主诉无法进行性交。4例男性（1.8%）经标准化诊断程序显示仅存在严重阴茎弯曲，导致无法性交；3例男性（1.4%）因疼痛而性交不满意。7例男性（3.1%）报告阴茎远端疲软，其中4例经动态海绵体测压和海绵体造影显示存在静脉闭塞功能障碍。在56例主诉完全丧失勃起功能的男性中，51例对海绵体内注射前列腺素E1无反应，27例（48.2%）经海绵体动脉双功超声检查显示动脉血流异常，47例（83.9%）根据海绵体测压标准有静脉闭塞功能障碍的证据，33例（58.9%）也有海绵体造影的相关证据。56例阳痿患者中有15例（26.8%）可见斑块相关的静脉引流，相当于所有海绵体造影异常病例的45.5%。
31.5%的患者性功能障碍可评估，阳痿和勃起丧失的主要原因是静脉闭塞功能障碍。
