Mutzner F, Amgwerd R, Gessner U
Schweiz Med Wochenschr. 1977 Jul 16;107(28):992-4.
A retrospective study is presented on 225 selected patients with local primary carcinoma of the breast treated from 1963 to 1973 at the Surgical Clinic of the Cantonal Hospital, St. Gallen, Switzerland. All patients were under 70 years old. The results are compared of our two therapies, namely radical mastectomy of Halsted and a modified radical mastectomy consisting of mastectomy with dissection of the axilla but without removing the pectoral muscle. Both operations were followed by postoperative irradiation. In view of the short postoperative interval after modified radical mastectomy (from 1969), a five-year diseasefree survival is indicated. There was no statistically significant difference between the two therapies. Depending on age, patients with histologically negative lymph nodes of the axilla had a probability of 45-60% for 5-year diseasefree survival, against only 15-40% for those with positive axillary lymph nodes. The quality of survival is deemed important, and the authors therefore recommend the modified radical mastectomy, which disfigures a woman less than the Halsted operation.
本文对1963年至1973年期间在瑞士圣加仑州立医院外科诊所接受治疗的225例局部原发性乳腺癌患者进行了回顾性研究。所有患者年龄均在70岁以下。比较了两种治疗方法的结果，即哈尔斯德根治性乳房切除术和一种改良根治性乳房切除术，后者包括乳房切除术加腋窝清扫但不切除胸肌。两种手术均在术后进行放疗。鉴于改良根治性乳房切除术（自1969年起）术后间隔时间较短，给出了五年无病生存率。两种治疗方法之间无统计学显著差异。根据年龄，腋窝淋巴结组织学检查阴性的患者五年无病生存概率为45% - 60%，而腋窝淋巴结阳性的患者仅为15% - 40%。生存质量被认为很重要，因此作者推荐改良根治性乳房切除术，因为它对女性身体外观的破坏比哈尔斯德手术小。
