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对自由行走猫的脊髓神经节体感神经元进行长期单位记录。

Long-term unit recording from somatosensory neurons in the spinal ganglia of the freely walking cat.

作者信息

Loeb G E, Bak M J, Duysens J

出版信息

Science. 1977 Sep 16;197(4309):1192-4. doi: 10.1126/science.897663.

DOI:10.1126/science.897663
PMID:897663
Abstract

A new technique has been developed for stable, long-term recording from groups of individual primary afferent neurons in the freely walking cat. A number of fine, flexible wires are inserted into dorsal root ganglia via a small laminotomy in the lumbar spine. The cut end of each wire can record stable and separable action potentials from one to three dorsal root ganglion neurons; each unit has typically held for 1 to 4 days. A broad range of myelinated somatosensory afferent (conduction velocities of 30 to 120 meters per second) have been studies during locomotion. Most cutaneous and proprioceptive afferent studied have been sensitive monitors of complex combinations of step-cycle components, and their firing patterns would often have been difficult to predict from existing information.

摘要

一种新技术已被开发出来,用于对自由行走的猫的单个初级传入神经元群进行稳定、长期的记录。通过腰椎的小切口椎板切除术,将许多细的、柔性电线插入背根神经节。每根电线的切割端可以记录来自一到三个背根神经节神经元的稳定且可分离的动作电位;每个单元通常能保持1至4天。在运动过程中,已经对广泛的有髓躯体感觉传入神经(传导速度为每秒30至120米)进行了研究。所研究的大多数皮肤和本体感觉传入神经都是步周期成分复杂组合的敏感监测器,而且根据现有信息,它们的放电模式通常很难预测。

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